Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM002061)
DM Name	Formoterol glucuronide metabolite 2

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
UDP-glucuronosyltransferase 1A1 (UGT1A1)	DME0004	Formoterol	Conjugation - O-Glucuronidation	Formoterol	[1] , [2]
UDP-glucuronosyltransferase 1A8 (UGT1A8)	DME0064	Formoterol	Conjugation - O-Glucuronidation	Formoterol	[1] , [2]
UDP-glucuronosyltransferase 1A9 (UGT1A9)	DME0042	Formoterol	Conjugation - O-Glucuronidation	Formoterol	[1] , [2]
UDP-glucuronosyltransferase 2B15 (UGT2B15)	DME0049	Formoterol	Conjugation - O-Glucuronidation	Formoterol	[1] , [2]
UDP-glucuronosyltransferase 2B7 (UGT2B7)	DME0040	Formoterol	Conjugation - O-Glucuronidation	Formoterol	[1] , [2]

Full List of Drug(s) That Produce This DM By Metabolism
Formoterol		DR0744	Approved		Asthma

References
1	Mass balance and metabolism of [(3)H]Formoterol in healthy men after combined i.v. and oral administration-mimicking inhalation Drug Metab Dispos. 1999 Oct;27(10):1104-16.
2	FDA Approved Drug Products: Perforomist? inhalation solution

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