Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM003988)
DM Name	3-OH-ABA

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 1A1 (CYP1A1)	DME0006	Nitrobenzanthrone	Reduction - Reduction	Nitrobenzanthrone	[1]
Cytochrome P450 1A2 (CYP1A2)	DME0003	Nitrobenzanthrone	Reduction - Reduction	Nitrobenzanthrone	[1]
Quinone reductase 1 (NQO1)	DME0097	Nitrobenzanthrone	Reduction - Reduction	Nitrobenzanthrone	[1]

DME(s) Metabolizing This DM

DME Name	DME ID	Product	Reaction	Related Drug	REF
Arylamine N-acetyltransferase (NAT)	DME1321	3-Aco-ABA	Unclear - Unclear	Nitrobenzanthrone	[1]
N-acetyltransferase 1 (NAT1)	DME0050	2-(2'-deoxyguanosin-N2-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]
N-acetyltransferase 1 (NAT1)	DME0050	N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]
N-acetyltransferase 2 (NAT2)	DME0051	2-(2'-deoxyguanosin-N2-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]
N-acetyltransferase 2 (NAT2)	DME0051	N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]
Sulfotransferase 1A1 (SULT1A1)	DME0008	2-(2'-deoxyguanosin-N2-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]
Sulfotransferase 1A1 (SULT1A1)	DME0008	N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]
Sulfotransferase 1A1 (SULT1A1)	DME0008	3-OS-ABA	Unclear - Unclear	Nitrobenzanthrone	[1]
Sulfotransferase 1A2 (SULT1A2)	DME0062	2-(2'-deoxyguanosin-N2-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]
Sulfotransferase 1A2 (SULT1A2)	DME0062	N-(2'-deoxyguanosin-8-yl)-3-aminobenzanthrone	Unclear - Unclear	Nitrobenzanthrone	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Nitrobenzanthrone		DR0010	Investigative		Discovery agent

References
1	Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells

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