General Information of Drug Metabolite (DM) (ID: DM004379)
DM Name
Metoclopramide hydrochloride Metabolite M4
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
Cytochrome P450 1A2 (CYP1A2) DME0003 Oxidation - Oxidationn Metoclopramide hydrochloride [1]
Cytochrome P450 2C9 (CYP2C9) DME0019 Oxidation - Oxidationn Metoclopramide hydrochloride [1]
Cytochrome P450 2D6 (CYP2D6) DME0009 Oxidation - Oxidationn Metoclopramide hydrochloride [1]
Cytochrome P450 3A4 (CYP3A4) DME0001 Oxidation - Oxidationn Metoclopramide hydrochloride [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME0021 Oxidation - Oxidationn Metoclopramide hydrochloride [1]
Full List of Drug(s) That Produce This DM By Metabolism
Metoclopramide hydrochloride DR1068 Approved Functional nausea/vomiting
References
1 Identification of novel metoclopramide metabolites in humans: in vitro and in vivo studies

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