General Information of Drug Metabolite (DM) (ID: DM004544)
DM Name
O-Desmethylnaproxen acyl glucuronide
Full List of Drug-Metabolizing Enzyme (DME) Related to This DM
DME(s) Producing This DM through Metabolism
DME Name DME ID Reactant Reaction Related Drug REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME0004 Conjugation - Glucuronidation Naproxen [1]
UDP-glucuronosyltransferase 1A10 (UGT1A10) DME0075 Conjugation - Glucuronidation Naproxen [1]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DME0041 Conjugation - Glucuronidation Naproxen [1]
UDP-glucuronosyltransferase 1A6 (UGT1A6) DME0072 Conjugation - Glucuronidation Naproxen [1]
UDP-glucuronosyltransferase 1A7 (UGT1A7) DME0065 Conjugation - Glucuronidation Naproxen [1]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME0042 Conjugation - Glucuronidation Naproxen [1]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME0040 Conjugation - Glucuronidation Naproxen [1]
Full List of Drug(s) That Produce This DM By Metabolism
Naproxen DR1130 Approved Rheumatoid arthritis
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.