Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM019432)
DM Name	Other imatinib metabolites

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Cytochrome P450 1A2 (CYP1A2)	DME0003	Imatinib	Unclear - Unclear	Imatinib	[1]
Cytochrome P450 2C8 (CYP2C8)	DME0018	Imatinib	Unclear - Unclear	Imatinib	[1]
Cytochrome P450 2C9 (CYP2C9)	DME0019	Imatinib	Unclear - Unclear	Imatinib	[1]
Cytochrome P450 2D6 (CYP2D6)	DME0009	Imatinib	Unclear - Unclear	Imatinib	[1]
Mephenytoin 4-hydroxylase (CYP2C19)	DME0021	Imatinib	Unclear - Unclear	Imatinib	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Imatinib		DR3390	Phase 3		Mantle cell lymphoma

References
1	Role of cytochrome P450 activity in the fate of anticancer agents and in drug resistance: focus on tamoxifen, paclitaxel and imatinib metabolism

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