Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000466)
Formula Reactant Bromperidol Product 4-fluorobenzoyl-propionic acid (FBPA)
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2E1 (CYP2E1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000465 Bromperidol Bromperidol pyridinium Unclear Bromperidol [1]
MR000464 Bromperidol Bromperidol to bromperidol 1,2,3,6-tetrahydropyridine Other reaction - Dehydration Bromperidol [1]
MR000463 Bromperidol Reduced bromperidol Oxidation - N-Dealkylation Bromperidol [1]
References
1 Involvement of CYP3A4 in the metabolism of bromperidol in vitro. Pharmacol Toxicol. 2000 Mar;86(3):145-8.

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