Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR000587)
Formula
CYP2C9 ...
SVG example
Hydroxylation
Reactant Celecoxib Product Hydroxycelecoxib
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000588 Celecoxib Celecoxib glucuronide Conjugation - Glucuronidation Celecoxib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000585 Hydroxycelecoxib Carboxycelecoxib Unclear Celecoxib [1]
References
1 Celecoxib pathways: pharmacokinetics and pharmacodynamics. Pharmacogenet Genomics. 2012 Apr;22(4):310-8.

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