Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001468)
Formula Reactant Levobupivacaine Product 3-hydroxy levobupivacaine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - N-Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001469 Levobupivacaine Desbutyl levobupivacaine Oxidation - Deamination Levobupivacaine [1]
MR001470 Levobupivacaine N-desbutylbupivacaine Unclear Levobupivacaine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001467 3-hydroxy levobupivacaine . Conjugation - Glucuronidation Levobupivacaine [1]
References
1 Clinical profile of levobupivacaine in regional anesthesia: A systematic review. J Anaesthesiol Clin Pharmacol. 2013 Oct;29(4):530-9.

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