Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001469)
Formula Reactant Levobupivacaine Product Desbutyl levobupivacaine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001468 Levobupivacaine 3-hydroxy levobupivacaine Oxidation - N-Dealkylation Levobupivacaine [1]
MR001470 Levobupivacaine N-desbutylbupivacaine Unclear Levobupivacaine [1]
References
1 Clinical profile of levobupivacaine in regional anesthesia: A systematic review. J Anaesthesiol Clin Pharmacol. 2013 Oct;29(4):530-9.

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