Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001581)
Formula
CYP2C19 ...
SVG example
Oxidative Deamination
Reactant N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide Product 2,6-dichlorophenol
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - Oxidative Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001583 Lofexidine N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide Oxidation - Hydroxylation Lofexidine [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001582 N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide 2-(2,6-dichlorophenoxy) propionic acid Oxidation - Oxidative Deamination Lofexidine [1]
References
1 DrugBank(Pharmacology-Metabolism)Lofexidine

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