Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001583)
Formula
CYP2C19 ...
SVG example
Hydroxylation
Reactant Lofexidine Product N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001581 N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide 2,6-dichlorophenol Oxidation - Oxidative Deamination Lofexidine [1]
MR001582 N-(2-aminoethyl)-2-(2,6-dichlorophenoxy)propanamide 2-(2,6-dichlorophenoxy) propionic acid Oxidation - Oxidative Deamination Lofexidine [1]
References
1 DrugBank(Pharmacology-Metabolism)Lofexidine

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