Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001611)
Formula	CYP2D6 Hydroxylation
	Reactant	Meclizine	Product	Meclizine metabolite M1
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 2D6 (CYP2D6)				DME Info
Metabolic Type	Oxidation - Hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR001612	Meclizine	Meclizine metabolite M2	Oxidation - Benzylic Oxidation	Meclizine	[1]
MR001610	Meclizine	Norchlorcyclizine	Oxidation - Hydroxylation	Meclizine	[1]

References
1	Meclizine metabolism and pharmacokinetics: formulation on its absorption. J Clin Pharmacol. 2012 Sep;52(9):1343-9.

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