Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001612)
Formula
SVG example
Benzylic Oxidation
Reactant Meclizine Product Meclizine metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Benzylic Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001611 Meclizine Meclizine metabolite M1 Oxidation - Hydroxylation Meclizine [1]
MR001610 Meclizine Norchlorcyclizine Oxidation - Hydroxylation Meclizine [1]
References
1 Meclizine metabolism and pharmacokinetics: formulation on its absorption. J Clin Pharmacol. 2012 Sep;52(9):1343-9.

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