Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001668)
Formula
CYP1A2 ...
SVG example
8-Hydroxylation
Reactant N-desmethylmianserin Product 8-hydroxy-N-desmethylmianserin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - 8-Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001670 Mianserin N-desmethylmianserin Oxidation - N-Oxidation Mianserin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001667 8-hydroxyminaserin 8-hydroxy-N-desmethylmianserin Oxidation - N-Dealkylation Mianserin [1]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.