Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001667)
Formula
CYP2C19 ...
SVG example
N-Dealkylation
Reactant 8-hydroxyminaserin Product 8-hydroxy-N-desmethylmianserin
Reactant Info Product Info
Metabolic Enzyme Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - N-Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001669 Mianserin 8-hydroxyminaserin Oxidation - Hydroxylation Mianserin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001668 N-desmethylmianserin 8-hydroxy-N-desmethylmianserin Oxidation - 8-Hydroxylation Mianserin [1]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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