Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001672)
Formula
CYP3A4 ...
SVG example
Hydroxylation
Reactant Mianserin Product (R)-mianserin,8-hydroxy
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001673 Mianserin (R)-mianserin,N-Desmethyl Oxidation - N-Dealkylation Mianserin [1]
MR001671 Mianserin (R)-mianserin,N-oxide Oxidation - N-Oxidation Mianserin [1]
MR001669 Mianserin 8-hydroxyminaserin Oxidation - Hydroxylation Mianserin [1]
MR001670 Mianserin N-desmethylmianserin Oxidation - N-Oxidation Mianserin [1]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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