General Information of This Metabolic Reaction (MR) (ID: MR001673)
Formula
CYP2D6 ...
SVG example
N-Dealkylation
Reactant Mianserin Product (R)-mianserin,N-Desmethyl
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - N-Dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001672 Mianserin (R)-mianserin,8-hydroxy Oxidation - Hydroxylation Mianserin [1]
MR001671 Mianserin (R)-mianserin,N-oxide Oxidation - N-Oxidation Mianserin [1]
MR001669 Mianserin 8-hydroxyminaserin Oxidation - Hydroxylation Mianserin [1]
MR001670 Mianserin N-desmethylmianserin Oxidation - N-Oxidation Mianserin [1]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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