Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001669)
Formula
CYP2D6 ...
SVG example
Hydroxylation
Reactant Mianserin Product 8-hydroxyminaserin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001672 Mianserin (R)-mianserin,8-hydroxy Oxidation - Hydroxylation Mianserin [1]
MR001673 Mianserin (R)-mianserin,N-Desmethyl Oxidation - N-Dealkylation Mianserin [1]
MR001671 Mianserin (R)-mianserin,N-oxide Oxidation - N-Oxidation Mianserin [1]
MR001670 Mianserin N-desmethylmianserin Oxidation - N-Oxidation Mianserin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001667 8-hydroxyminaserin 8-hydroxy-N-desmethylmianserin Oxidation - N-Dealkylation Mianserin [1]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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