Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001874)
Formula
SVG example
Reactant Oxtriphylline Product 1,3-Dimethyluric acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001873 Oxtriphylline 1-Methyluric acid Unclear Oxtriphylline [1]
MR001875 Oxtriphylline 3-Methylxanthine Unclear Oxtriphylline [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004947 Theophylline 1,3-dimethyluric acid Oxidation - 8-hydroxylation Theophylline [2]
References
1 Polymorphisms in the CYP1A2 gene and theophylline metabolism in patients with asthma Clin Pharmacol Ther. 2003 May;73(5):468-74. doi: 10.1016/s0009-9236(03)00013-4.
2 Theophylline metabolism in human liver microsomes: inhibition studies. J Pharmacol Exp Ther. 1996 Mar;276(3):912-7.

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