Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002006)
Formula
SVG example
S-Oxidation
Reactant Perphenazine Product Perphenazine sulfoxide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - S-Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002007 Perphenazine Hydroxychlorpromazine Oxidation - Hydroxylation Perphenazine [1]
MR002008 Perphenazine Mesoridazine Unclear Perphenazine [1]
MR002005 Perphenazine N-Dealkylated perphenazine Oxidation - N-Dealkylation Perphenazine [2]
References
1 American Society of Health System Pharmacists; AHFS Drug Information 2010. Bethesda, MD. (2010), p. 2511
2 Anti-Parkinson's disease drugs and pharmacogenetic considerations Expert Opin Drug Metab Toxicol. 2013 Jul;9(7):859-74. doi: 10.1517/17425255.2013.789018.

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