Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002042)
Formula	Reactant	Pinacidil	Product	M-2
Formula	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)				DME Info
Metabolic Type	Oxidation - N-Oxidation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR002044	Pinacidil	M3 and M4	Unclear	Pinacidil	[1]
MR002043	Pinacidil	Pinacidil amide	Unclear	Pinacidil	[1]

References
1	Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil. Biochemistry. 2002 Feb 26;41(8):2712-8.

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