General Information of This Metabolic Reaction (MR) (ID: MR002043)
Formula
Reactant Pinacidil Product Pinacidil amide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002042 Pinacidil M-2 Oxidation - N-Oxidation Pinacidil [1]
MR002044 Pinacidil M3 and M4 Unclear Pinacidil [1]
References
1 Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil. Biochemistry. 2002 Feb 26;41(8):2712-8.

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