Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002299)
Formula Reactant Thiophene-4,5-epoxide Product Suprofen metabolite M1 Intermediate
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002305 Suprofen Thiophene-4,5-epoxide Unclear Suprofen [1]
MR006192 Tienilic acid Thiophene-4,5-epoxide Oxidation - Epoxidation Tienilic acid [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002300 Thiophene-4,5-epoxide Suprofen metabolite M2 Unclear Suprofen [1]
MR002301 Thiophene-4,5-epoxide Suprofen metabolite M3 Unclear Suprofen [1]
MR002302 Thiophene-4,5-epoxide Suprofen metabolite M4 Unclear Suprofen [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002304 Suprofen metabolite M1 Intermediate 5-OH-suprofen Unclear Suprofen [1]
MR002303 Suprofen metabolite M1 Intermediate Suprofen metabolite M1 Oxidation - N-Dealkylation Suprofen [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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