Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002306)
Formula
SVG example
Oxidation
Reactant Suprofen Product 5-OH-suprofen
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C9 (CYP2C9) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002307 Suprofen Suprofen glucuronide Conjugation - Glucuronidation Suprofen [1]
MR002305 Suprofen Thiophene-4,5-epoxide Unclear Suprofen [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002304 Suprofen metabolite M1 Intermediate 5-OH-suprofen Unclear Suprofen [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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