Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002307)
Formula Reactant Suprofen Product Suprofen glucuronide
Reactant Info Product Info
Metabolic Enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002306 Suprofen 5-OH-suprofen Oxidation - Oxidation Suprofen [1]
MR002305 Suprofen Thiophene-4,5-epoxide Unclear Suprofen [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.