Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR002471)
Formula
CYP2D6 ...
SVG example
Mono-N-Demethylation
Reactant Ulipristal Product PGL4002
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Mono-N-Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002470 Ulipristal Epoxide ulipristal acetate Unclear Ulipristal [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR002469 PGL4002 PGL-4004 Oxidation - Di-N-Demethylation Ulipristal [1]
References
1 Pharmacokinetics, toxicological and clinical aspects of ulipristal acetate: insights into the mechanisms implicated in the hepatic toxicity Drug Metab Rev. 2021 Aug;53(3):375-383. doi: 10.1080/03602532.2021.1917599.

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