General Information of This Metabolic Reaction (MR) (ID: MR003508)
Formula
SVG example
Reactant DOPA Product DOPP
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009123 ABBV-951 Levodopa Unclear - Unclear ABBV-951 [1]
MR005862 L-tyrosine DOPA Oxidation - Hydrolyzationn L-tyrosine [2]
MR003503 L-Tyrosine DOPA Unclear L-phenylalanine [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003504 DOPA 3,4-dihydroxyphenylpropionic acid(DPPA) Unclear L-phenylalanine [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR003509 DOPP DOPL Unclear L-phenylalanine [3]
References
1 Scalable Asymmetric Syntheses of Foslevodopa and Foscarbidopa Drug Substances for the Treatment of Parkinson's Disease
2 Potent inhibitory effects of tyrosine metabolites on dihydropteridine reductase from human and sheep liver
3 Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine Res Microbiol. 2007 Jul-Aug;158(6):506-11. doi: 10.1016/j.resmic.2007.04.008.

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