Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004711)
Formula
SVG example
Reactant Metoprolol succinate Product H105/22
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004707 Metoprolol succinate Alpha-Hydroxymetoprolol Oxidation - Hydrolyzationn Metoprolol succinate [1]
MR004714 Metoprolol succinate Deisopropylmetoprolol Oxidation - N-dealkylation Metoprolol succinate [2]
MR004715 Metoprolol succinate H104/83 Unclear Metoprolol succinate [3]
MR004713 Metoprolol succinate O-Demethylmetoprolol Oxidation - O-dealkylation Metoprolol succinate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004720 Metoprolol tartrate H105/22 Unclear Metoprolol tartrate [3]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004712 H105/22 H107/04 Unclear Metoprolol succinate [3]
MR004721 H105/22 H107/04 Unclear Metoprolol tartrate [3]
References
1 DrugBank(Pharmacology-Metabolism):Metoprolol succinate
2 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.
3 Metabolism of metoprolol in the rat in vitro and in vivo

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