Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR004720)
Formula
SVG example
Reactant Metoprolol tartrate Product H105/22
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004716 Metoprolol tartrate Alpha-Hydroxymetoprolol Oxidation - Hydrolyzationn Metoprolol tartrate [1]
MR004723 Metoprolol tartrate Deisopropylmetoprolol Oxidation - N-dealkylation Metoprolol tartrate [2]
MR004724 Metoprolol tartrate H104/83 Unclear Metoprolol tartrate [1]
MR004722 Metoprolol tartrate O-Demethylmetoprolol Oxidation - O-dealkylation Metoprolol tartrate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004711 Metoprolol succinate H105/22 Unclear Metoprolol succinate [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004712 H105/22 H107/04 Unclear Metoprolol succinate [1]
MR004721 H105/22 H107/04 Unclear Metoprolol tartrate [1]
References
1 Metabolism of metoprolol in the rat in vitro and in vivo
2 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.

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