Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR005081)
Formula
SVG example
Oxidationn
Reactant Halothane Product Bromide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2E1 (CYP2E1) DME Info
Metabolic Type Oxidation - Oxidationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005084 Halothane 1-chloro-2,2,2-trifluoroethanide Reduction - Dehalogenation Halothane [1], [2]
MR005083 Halothane 2-chloro-1,1-difluoroethene Reduction - Dehalogenation Halothane [1], [2]
MR005086 Halothane Chlorotrifluoroethane Reduction - Dehalogenation Halothane [2]
MR005082 Halothane Trifluoroacetic acid Oxidation - Oxidationn Halothane [3]
MR005085 Halothane Trifluoroacetyl chloride Reduction - Dehalogenation Halothane [2]
References
1 Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448.
2 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.
3 DrugBank(Pharmacology-Metabolism):Halothane

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