Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006464)
Formula
CYP3A4 ...
SVG example
N-dealkylation
Reactant SHP-620 Product VP 44469
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005532 Maribavir VP 44469 Oxidation - N-Dealkylation Maribavir [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005533 VP 44469 Maribavir M1 Conjugation - Glucuronidation conjugation Maribavir [2]
References
1 Effect of ketoconazole on the pharmacokinetics of maribavir in healthy adults
2 Elucidation of Metabolic and Disposition Pathways for Maribavir in Nonhuman Primates through Mass Balance and Semi-Physiologically Based Modeling Approaches

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.