Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006476)
Formula	UGT1A3
	Reactant	TAK-875	Product	T-167642
	Reactant	Reactant Info	Product	Product Info
Metabolic Enzyme	UDP-glucuronosyltransferase 1A3 (UGT1A3)				DME Info

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006475	TAK-875	Fasiglifam-G	Conjugation - Conjugation	TAK-875	[1]
MR006474	TAK-875	Fasiglifam-Tau	Unclear	TAK-875	[1]
MR006472	TAK-875	TAK-875 Metabolite M-I	Unclear	TAK-875	[1]

References
1	Disposition and metabolism of the G protein-coupled receptor 40 agonist TAK-875 (fasiglifam) in rats, dogs, and humans. Xenobiotica. 2019 Apr;49(4):433-445.

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