Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR006475)
Formula	CYP3A4 ... Conjugation
	Reactant	TAK-875		Product	Fasiglifam-G
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)					DME Info
Metabolic Enzyme	Cytochrome P450 3A5 (CYP3A5)					DME Info
Metabolic Type	Conjugation - Conjugation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR006474	TAK-875	Fasiglifam-Tau	Unclear	TAK-875	[1]
MR006476	TAK-875	T-167642	Unclear	TAK-875	[1]
MR006472	TAK-875	TAK-875 Metabolite M-I	Unclear	TAK-875	[1]

References
1	Disposition and metabolism of the G protein-coupled receptor 40 agonist TAK-875 (fasiglifam) in rats, dogs, and humans. Xenobiotica. 2019 Apr;49(4):433-445.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.