Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006587)
Formula
CYP2D6 ...
SVG example
4-hydroxylation
Reactant Clonidine Product 4-Hydroxyclonidine
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Oxidation - 4-hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006588 Clonidine 2,6-dichlorophenylguanidine Unclear Clonidine [1]
MR006589 Clonidine 4,5-dehydroclonidine Unclear Clonidine [1]
MR006590 Clonidine 4-oxoclonidine Unclear Clonidine [1]
References
1 The metabolism of N,N'-dimethylclonidine by rat liver microsomes [proceedings]

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