General Information of This Metabolic Reaction (MR) (ID: MR006630)
Formula Reactant 3-MT Product MHPA
Reactant Info Product Info
Metabolic Enzyme Monoamine oxidase (MAO) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006629 Dopamine hydrochloride 3-MT Unclear Dopamine hydrochloride [1]
MR001485 Dopamine 3-Methoxytyramine Conjugation - O-Methylation Levodopa [2]
MR008913 Dopamine 3-methoxytyramine Unclear - Unclear Docarpamine [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001492 3-Methoxytyramine 3-methoxy-4-hydroxyacetaldehyde Oxidation - Oxidative Deamination Levodopa [2]
MR008914 3-methoxytyramine Homovanillic acid Unclear - Unclear Docarpamine [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006631 MHPA HVA Unclear Dopamine hydrochloride [1]
References
1 Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain
2 DrugBank(Pharmacology-Metabolism)Levodopa
3 Metabolism of a new orally active dopamine prodrug, N-(N-acetyl-L-methionyl)-O,O-bis(ethoxycarbonyl)dopamine (TA-870) and dopamine after oral administration to rats and dogs

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