Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001492)
Formula Reactant 3-Methoxytyramine Product 3-methoxy-4-hydroxyacetaldehyde
Reactant Info Product Info
Metabolic Enzyme Monoamine oxidase (MAO) DME Info
Metabolic Type Oxidation - Oxidative Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006629 Dopamine hydrochloride 3-MT Unclear Dopamine hydrochloride [1]
MR001485 Dopamine 3-Methoxytyramine Conjugation - O-Methylation Levodopa [2]
MR008913 Dopamine 3-methoxytyramine Unclear - Unclear Docarpamine [3]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006630 3-MT MHPA Unclear Dopamine hydrochloride [1]
MR008914 3-methoxytyramine Homovanillic acid Unclear - Unclear Docarpamine [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001493 3-methoxy-4-hydroxyacetaldehyde Homovanillic acid Oxidation - Oxidation Levodopa [2]
References
1 Membrane bound catechol-O-methytransferase is the dominant isoform for dopamine metabolism in PC12 cells and rat brain
2 DrugBank(Pharmacology-Metabolism)Levodopa
3 Metabolism of a new orally active dopamine prodrug, N-(N-acetyl-L-methionyl)-O,O-bis(ethoxycarbonyl)dopamine (TA-870) and dopamine after oral administration to rats and dogs

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