Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR006891)
Formula
SVG example
N-demethylation
Reactant Lomefloxacin Product N-Desmethylamifloxacin
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011860 Amifloxacin N-desmethyl-Amifloxacin Unclear - Unclear Amifloxacin [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006892 N-Desmethylamifloxacin Lomefloxacin glucuronide metabolite Conjugation - Glucuronidation Lomefloxacin [2]
References
1 In vitro activities of amifloxacin and two of its metabolites
2 Pubchem:Lomefloxacin

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