Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009357)
Formula
CYP2E1 ...
SVG example
Unclear
Reactant TAK-802 Metabolite M-IV Product TAK-802 Metabolite M-II
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2E1 (CYP2E1) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009356 TAK-802 TAK-802 Metabolite M-IV Reduction - Reduction TAK-802 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009359 TAK-802 Metabolite M-I TAK-802 Metabolite M-II Unclear - Unclear TAK-802 [2]
References
1 Main metabolic pathways of TAK-802, a novel drug candidate for voiding dysfunction, in humans: the involvement of carbonyl reduction by 11-hydroxysteroid dehydrogenase 1
2 Disposition of the new potent acetylcholinesterase inhibitor 8-[3-[1-[(3-fluorophenyl)methyl]-4-piperidiny]-1-oxopropyl]-1, 2, 5, 6-tetrahydro-4H-pyrrolo [3, 2, 1-ij] quinolin-4-one (TAK-802) in rats, dogs and monkeys

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