Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009948)
Formula
SVG example
Unclear
Reactant Cyclophosphamide Product Dechloroethyl cyclophosphamide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009942 Cyclophosphamide 4-Hydroxycyclophosphamide Unclear - Unclear Cyclophosphamide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012907 Cyclobenzaprine Dechloroethyl cyclophosphamide Unclear Cyclobenzaprine [2]
MR004662 Ifosfamide 3-Dechloroethylifosfamide Unclear Ifosfamide [3], [4]
References
1 Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism
2 U. S. FDA Label -Cyclobenzaprine
3 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.
4 The KEGG resource for deciphering the genome

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