| General Information of This Metabolic Reaction (MR) (ID:
MR012008) |
| Formula |
Reactant |
Imatinib |
Product |
Other imatinib metabolites |
|
Reactant Info
|
Product Info
|
|
Metabolic Enzyme
|
Cytochrome P450 1A2 (CYP1A2)
|
DME Info
|
|
Cytochrome P450 2C8 (CYP2C8)
|
DME Info
|
|
Cytochrome P450 2C9 (CYP2C9)
|
DME Info
|
|
Mephenytoin 4-hydroxylase (CYP2C19)
|
DME Info
|
|
Cytochrome P450 2D6 (CYP2D6)
|
DME Info
|
|
Metabolic Type
|
Unclear
-
Unclear
|
|
|
|
|
|
|
|
| Other MR(s) Related to The Reactant of This MR |
|
Other MR(s) That Metabolize The Reactant of This MR
|
|
|
| References |
| 1 |
Role of cytochrome P450 activity in the fate of anticancer agents and in drug resistance: focus on tamoxifen, paclitaxel and imatinib metabolism
|
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