Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR012497)
Formula	CYP3A4 ... Unclear
	Reactant	PTC299		Product	O-Desmethyl emvododstat
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 3A4 (CYP3A4)					DME Info
	Cytochrome P450 2C8 (CYP2C8)					DME Info
	Mephenytoin 4-hydroxylase (CYP2C19)					DME Info
	Cytochrome P450 2D6 (CYP2D6)					DME Info
Metabolic Type	Unclear - Unclear

Other MR(s) Related to The Product of This MR

Other MR(s) That Metabolize The Produtc of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR012498	O-Desmethyl emvododstat	O-Desmethyl emvododstat glucuronide	Unclear - Unclear	PTC299	[1]

References
1	In vitro metabolism, pharmacokinetics and drug interaction potentials of emvododstat, a DHODH inhibitor

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