Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012847)
Formula
SVG example
Reactant Androstenedione Product 11beta-hydroxyandrostenedione
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012852 Androstenedione 5alpha-dihydroandrostenedione Unclear Androstenedione [1]
MR012850 Androstenedione 5alpha-dihydrotestosterone Unclear Androstenedione [1]
MR012849 Androstenedione 6beta-hydroxy-androstenedione Oxidation - Aliphatic hydroxylation Androstenedione [2]
MR012851 Androstenedione Testosterone Unclear Androstenedione [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012848 11beta-hydroxyandrostenedione 11beta-hydroxy-5alpha-androstanedione Unclear Androstenedione [3]
References
1 Androstenedione (a Natural Steroid and a Drug Supplement): A Comprehensive Review of Its Consumption, Metabolism, Health Effects, and Toxicity with Sex Differences
2 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.
3 11-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5-reductase yielding 11-hydroxy-5-androstanedione

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