General Information of This Metabolic Reaction (MR) (ID: MR012852)
Formula Reactant Androstenedione Product 5alpha-dihydroandrostenedione
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012847 Androstenedione 11beta-hydroxyandrostenedione Unclear Androstenedione [1]
MR012850 Androstenedione 5alpha-dihydrotestosterone Unclear Androstenedione [2]
MR012849 Androstenedione 6beta-hydroxy-androstenedione Oxidation - Aliphatic hydroxylation Androstenedione [3]
MR012851 Androstenedione Testosterone Unclear Androstenedione [2]
References
1 11-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5-reductase yielding 11-hydroxy-5-androstanedione
2 Androstenedione (a Natural Steroid and a Drug Supplement): A Comprehensive Review of Its Consumption, Metabolism, Health Effects, and Toxicity with Sex Differences
3 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.

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