Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013458)
Formula
SVG example
N-dealkylation
Reactant Etoperidone Product Etoperidone Metabolite M6
Reactant Info Product Info
Metabolic Type Oxidation - N-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013453 Etoperidone 1-(3-chlorophenyl) piperazine Unclear Etoperidone [1], [2]
MR013469 Etoperidone 1-(3-chlorophenyl) piperazine (M22) Oxidation - N-dealkylation Etoperidone [1]
MR013460 Etoperidone Etoperidone Metabolite M12 Hydrolysis - Hydrolysis Etoperidone [1]
MR013465 Etoperidone Etoperidone Metabolite M19 Oxidation - Oxidationn Etoperidone [1]
MR013442 Etoperidone Etoperidone Metabolite M2 Oxidation - Oxidationn Etoperidone [1], [2]
MR013466 Etoperidone Etoperidone Metabolite M20 Oxidation - Oxidationn Etoperidone [1]
MR013467 Etoperidone Etoperidone Metabolite M21 Oxidation - Oxidationn Etoperidone [1]
MR013468 Etoperidone Etoperidone Metabolite M4 Oxidation - Aromatic hydroxylation Etoperidone [1]
MR013451 Etoperidone Etoperidone Metabolite M5 Oxidation - Hydrolyzationn Etoperidone [1], [2]
MR013455 Etoperidone Etoperidone Metabolite N6 Unclear Etoperidone [1]
MR013464 Etoperidone N-oxide etoperidone Oxidation - Oxidationn Etoperidone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013459 Etoperidone Metabolite M6 Etoperidone Metabolite M9 Unclear Etoperidone [1]
MR013457 Etoperidone Metabolite M6 Etoperidone Metabolite N10 Unclear Etoperidone [1]
MR013456 Etoperidone Metabolite M6 Etoperidone Metabolite N7 Unclear Etoperidone [1]
References
1 Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man
2 In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone. Xenobiotica. 2002 Nov;32(11):949-62.

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