Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013451)
Formula
SVG example
Hydrolyzationn
Reactant Etoperidone Product Etoperidone Metabolite M5
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013453 Etoperidone 1-(3-chlorophenyl) piperazine Unclear Etoperidone [1], [2]
MR013469 Etoperidone 1-(3-chlorophenyl) piperazine (M22) Oxidation - N-dealkylation Etoperidone [1]
MR013460 Etoperidone Etoperidone Metabolite M12 Hydrolysis - Hydrolysis Etoperidone [1]
MR013465 Etoperidone Etoperidone Metabolite M19 Oxidation - Oxidationn Etoperidone [1]
MR013442 Etoperidone Etoperidone Metabolite M2 Oxidation - Oxidationn Etoperidone [1], [2]
MR013466 Etoperidone Etoperidone Metabolite M20 Oxidation - Oxidationn Etoperidone [1]
MR013467 Etoperidone Etoperidone Metabolite M21 Oxidation - Oxidationn Etoperidone [1]
MR013468 Etoperidone Etoperidone Metabolite M4 Oxidation - Aromatic hydroxylation Etoperidone [1]
MR013458 Etoperidone Etoperidone Metabolite M6 Oxidation - N-dealkylation Etoperidone [1]
MR013455 Etoperidone Etoperidone Metabolite N6 Unclear Etoperidone [1]
MR013464 Etoperidone N-oxide etoperidone Oxidation - Oxidationn Etoperidone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013452 Etoperidone Metabolite M5 Etoperidone Metabolite M8 Oxidation - Hydrolyzationn Etoperidone [1]
References
1 Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man
2 In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone. Xenobiotica. 2002 Nov;32(11):949-62.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.