Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013684)
Formula Reactant Carboxyl metabolite enzalutamide (M1) Product Enzalutamide metabolite M11
Reactant Info Product Info
Metabolic Type Conjugation - Acyl glucuronide conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013689 Indocyanine green Carboxyl metabolite enzalutamide (M1) Multi-steps Reaction - Amide Hydrolysis; Demethylation Enzalutamide [1], [2]
MR013683 N-desmethyl enzalutamide Carboxyl metabolite enzalutamide (M1) Unclear Enzalutamide [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013690 Carboxyl metabolite enzalutamide (M1) Enzalutamide metabolite M5 Unclear Enzalutamide [1]
References
1 Absorption, Distribution, Metabolism, and Excretion of the Androgen Receptor Inhibitor Enzalutamide in Rats and Dogs
2 Pharmacokinetic Aspects of the Two Novel Oral Drugs Used for Metastatic Castration-Resistant Prostate Cancer: Abiraterone Acetate and Enzalutamide

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.