Details of the Metabolic Reaction (MR) | INTEDE

General Information of This Metabolic Reaction (MR) (ID: MR013906)
Formula	CYP2D6 Hydroxylation
	Reactant	Flunarizine		Product	Flunarizine M2
	Reactant	Reactant Info		Product	Product Info
Metabolic Enzyme	Cytochrome P450 2D6 (CYP2D6)					DME Info
Metabolic Type	Oxidation - Hydroxylation

Other MR(s) Related to The Reactant of This MR

Other MR(s) That Metabolize The Reactant of This MR

MR ID	Reactant	Product	MR Type	Related Drug	REF
MR013905	Flunarizine	Flunarizine M1	Oxidation - N-desalkylation	Flunarizine	[1]
MR013907	Flunarizine	Flunarizine M3	Oxidation - N-desalkylation	Flunarizine	[1]

References
1	Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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