Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00973)
Xenobiotics Name
Diuron
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Herbicide
Structure
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3D MOL 2D MOL
PubChem CID
3120
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aldehyde oxidase (AOX1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Aldo-keto reductase 1C1 (AKR1C1) DME Info Homo sapiens [1]
Aldo-keto reductase 1C2 (AKR1C2) DME Info Homo sapiens [1]
Aldo-keto reductase 1C3 (AKR1C3) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2], [3]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [3]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [1]
Cytochrome P450 2A6 (CYP2A6) DME Info Homo sapiens [4]
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [4]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [4]
Cytochrome P450 3A7 (CYP3A7) DME Info Homo sapiens [2]
Leukotriene B4 omega-hydroxylase (CYP4F3) DME Info Homo sapiens [1]
Dipeptidyl peptidase IV (DPP4) DME Info Homo sapiens [1]
Estradiol 17-beta-dehydrogenase 2 (HSD17B2) DME Info Homo sapiens [1]
Ecto-5'-nucleotidase (NT5E) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
References
1 Diuron metabolites and urothelial cytotoxicity: in vivo, in vitro and molecular approaches. Toxicology. 2013 Dec 15;314(2-3):238-46.
2 Hierarchical cluster analysis of environmental pollutants through P450 induction in cultured hepatic cells. Ecotoxicol Environ Saf. 1996 Aug;34(3):205-15.
3 The inducibility of human cytochrome P450 1A by environmental-relevant xenobiotics in the human hepatoma derived cell line HepG2. Environ Toxicol Pharmacol. 2009 Nov;28(3):370-8.
4 Characterization of human cytochrome P450 induction by pesticides. Toxicology. 2012 Mar 29;294(1):17-26.

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