Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01257)
Xenobiotics Name
Clofibric acid
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Herbicide
Structure
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3D MOL 2D MOL
PubChem CID
2797
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 2A6 (CYP2A6) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Cytochrome P450 2C8 (CYP2C8) DME Info Homo sapiens [2]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [3]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [2]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info Homo sapiens [2]
References
1 CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers. Drug Metab Dispos. 2000 Nov;28(11):1321-6.
2 Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes. Pharm Res. 2005 Jan;22(1):71-8.
3 Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes. Drug Metab Dispos. 2005 Jul;33(7):1004-16.

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