Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01442)
Xenobiotics Name
Puag-haad
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
5281717
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [1]
Cytochrome P450 2C8 (CYP2C8) DME Info Homo sapiens [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [3]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [3]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [4]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [3]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [5]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 1A2 (CYP1A2) DME Info IC50 = 150 microM [1]
References
1 Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors. J Med Chem. 2002 Jan 3;45(1):160-4.
2 Effect of the interaction between lipoxygenase pathway and progesterone on the regulation of hydroxysteroid 11-Beta dehydrogenase 2 in cultured human term placental trophoblasts. Biol Reprod. 2008 Mar;78(3):514-20.
3 Inhibition of Pseudomonas aeruginosa and Escherichia coli O157:H7 biofilm formation by plant metabolite -viniferin. J Agric Food Chem. 2013 Jul 24;61(29):7120-6.
4 Stilbenes reduce Staphylococcus aureus hemolysis, biofilm formation, and virulence. Foodborne Pathog Dis. 2014 Sep;11(9):710-7.
5 Endometrial receptivity is affected in women with high circulating progesterone levels at the end of the follicular phase: a functional genomics analysis. Hum Reprod. 2011 Jul;26(7):1813-25.

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